Is HCG from Lumera Labs HPLC verified?

Yes. Every HCG lot Lumera Labs ships is HPLC-purity tested at synthesis and retested by Janoshik Analytical before release. The lot-specific Certificate of Analysis is published on the Lab Results page.

Is HCG sold for human use?

No. HCG is sold strictly as a laboratory reference standard for in-vitro research. It is not approved by Health Canada or the FDA for human use. Every order requires a research-use declaration.

HCG is lyophilized at synthesis, sealed under nitrogen, and shipped from Kelowna, BC at -20 C through cold-chain insulated packaging via Canada Post Xpresspost. Free shipping over $200 CAD. 24-48h transit Canada-wide.

Where can I see the COA for HCG?

Each shipment includes a lot-specific Certificate of Analysis. The current lot's COA is also published at https://lumerapeptide.com/lab-results/ and can be cross-referenced by the batch number printed on each vial.

Home / Catalog / Hormone / HCG 5000 mg

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Reproductive · Glycoprotein hormone

HCG

SKU LUM-HCG-5K · Heterodimeric glycoprotein · ~36,700 Da (heterodimer) · CAS 9002-61-3

Recombinant human chorionic gonadotropin — a heterodimeric glycoprotein hormone that activates the LH/CG receptor. Supplied lyophilized for in-vitro reproductive-axis research.

Purity (HPLC): ≥ 99.2%
Net peptide: 5.00 mg ± 2%
Endotoxin: < 0.5 EU/mg
Format: Lyophilized vial
Storage: −20 °C, desiccated
Shelf life: 24 months from MFG

$80CAD / 5000 mg vial

In stock · Lot 26-A031

Qty

Bulk 10+: $24 / vial

Add $200 for free cold-chain shipping

HPLC + MS verified per lot
Cold-chain to your door
COA bundled with shipment
Lot retains kept 5 years

Overview

Human chorionic gonadotropin (HCG) is a heterodimeric glycoprotein composed of an α-subunit (shared with LH, FSH, and TSH) and a unique β-subunit. It binds the LH/CG receptor on Leydig and granulosa cells with high affinity, driving steroidogenesis pathways.

Each vial is lyophilized and shipped cold-chain at −20 °C from our Kelowna facility. Reconstitute with sterile water or bacteriostatic water for in-vitro receptor studies.

Research applications

LH/CG-receptor binding affinity assays, Leydig-cell testosterone-secretion screens, granulosa-cell aromatase induction, and comparative gonadotropin pharmacology versus LH and recombinant FSH.

Sold for laboratory research only. This material is not a drug, food, or cosmetic and is not intended for diagnostic, therapeutic, or recreational use.

Identity

Parameter	Value
Sequence	α-subunit (shared with LH/FSH/TSH) + β-subunit (HCG-specific)
Molecular formula	Heterodimeric glycoprotein
Molecular weight	~36,700 Da (heterodimer)
CAS number	9002-61-3
Length	α 92 + β 145 residues

Quality

Test	Specification
HPLC purity	≥ 99.0% (lot LM-2645: ≥ 99% by SDS-PAGE)
Mass confirmation	ESI-MS within 0.5 Da
Net peptide content	≥ 80% by AAA
Endotoxin	< 0.5 EU/mg (LAL)
Bioburden	< 10 CFU/g
Residual TFA	< 1.0%

Lot LM-2645

Manufactured 04 Mar 2026 · Released 11 Mar 2026 · Tested by Lumera QC, Kelowna BC. Retain samples held under storage spec for five years from release date.

Verification

Method	Result
RP-HPLC at 220 nm	≥ 99% by SDS-PAGE main peak
ESI-MS (positive)	~36,700 Da (heterodimer)
Amino acid analysis	82.1% net peptide
LAL endotoxin	< 0.05 EU/mg
Karl Fischer (water)	2.8% w/w

Reconstitution

Allow vial to reach room temperature before opening (≥ 20 minutes). Reconstitute with 1.0–2.5 mL of sterile bacteriostatic water (0.9% benzyl alcohol). Inject solvent slowly down the inner wall of the vial; do not direct stream onto the lyophilized cake.

Swirl gently for 30 seconds. Do not vortex. Allow to dissolve for 5 minutes; clarity should be complete with no visible particulates.

Storage after reconstitution

Reconstituted solution is stable for 28 days at 2–8 °C in original vial. For longer storage, aliquot into low-binding tubes and hold at −80 °C; avoid repeated freeze-thaw cycles. Discard if turbidity, color change, or particulate matter is observed.