SKU LUM-HCG-5K · Heterodimeric glycoprotein · ~36,700 Da (heterodimer) · CAS 9002-61-3
Recombinant human chorionic gonadotropin — a heterodimeric glycoprotein hormone that activates the LH/CG receptor. Supplied lyophilized for in-vitro reproductive-axis research.
Purity (HPLC)
≥ 99.2%
Net peptide
5.00 mg ± 2%
Endotoxin
< 0.5 EU/mg
Format
Lyophilized vial
Storage
−20 °C, desiccated
Shelf life
24 months from MFG
$45CAD/ 5000 mg vial
In stock · Lot LM-2750
Qty
Add $300 for Free shipping
HPLC + MS verified per lot
~4 days to your door
COA bundled with shipment
Lot samples retained 5 years
Overview
Human chorionic gonadotropin (HCG) is a heterodimeric glycoprotein composed of an α-subunit (shared with LH, FSH, and TSH) and a unique β-subunit. It binds the LH/CG receptor on Leydig and granulosa cells with high affinity, driving steroidogenesis pathways.
Each vial is lyophilized and shipped ~4 days from our lab. Reconstitute with bacteriostatic water for in-vitro receptor studies.
Research applications
LH/CG-receptor binding affinity assays, Leydig-cell testosterone-secretion screens, granulosa-cell aromatase induction, and comparative gonadotropin pharmacology versus LH and recombinant FSH.
Sold for laboratory research only. This material is not a drug, food, or cosmetic and is not intended for diagnostic, therapeutic, or recreational use.
Identity
Parameter
Value
Sequence
α-subunit (shared with LH/FSH/TSH) + β-subunit (HCG-specific)
Molecular formula
Heterodimeric glycoprotein
Molecular weight
~36,700 Da (heterodimer)
CAS number
9002-61-3
Length
α 92 + β 145 residues
Quality
Test
Specification
HPLC purity
≥ 99% by SDS-PAGE (Pfizer/manufacturer)
Mass confirmation
ESI-MS within 0.5 Da
Net peptide content
≥ 80% by AAA
Endotoxin
< 0.5 EU/mg (LAL)
Bioburden
< 10 CFU/g
Residual TFA
< 1.0%
Lot LM-2750
Manufactured 04 Mar 2026 · Released 11 Mar 2026 · Tested by Lumera QC, Canada. Retain samples held under storage spec for five years from release date.
Verification
Method
Result
RP-HPLC at 220 nm
≥ 99% by SDS-PAGE main peak
ESI-MS (positive)
~36,700 Da (heterodimer)
Amino acid analysis
82.1% net peptide
LAL endotoxin
< 0.05 EU/mg
Karl Fischer (water)
2.8% w/w
Reconstitution
Allow vial to reach room temperature before opening (≥ 20 minutes). Reconstitute with 1.0–2.5 mL of sterile bacteriostatic water (0.9% benzyl alcohol). Inject solvent slowly down the inner wall of the vial; do not direct stream onto the lyophilized cake.
Swirl gently for 30 seconds. Do not vortex. Allow to dissolve for 5 minutes; clarity should be complete with no visible particulates.
Storage after reconstitution
Reconstituted solution is stable for 28 days at 2–8 °C in original vial. For longer storage, aliquot into low-binding tubes and hold at −80 °C; avoid repeated freeze-thaw cycles. Discard if turbidity, color change, or particulate matter is observed.
Selected references
Cole LA. Biological functions of hCG and hCG-related molecules. Reprod Biol Endocrinol. 2010;8:102.
Stenman UH et al. The classification, functions and clinical use of different isoforms of HCG. Hum Reprod Update. 2006;12(6):769–784.
Fournier T et al. Role of human chorionic gonadotropin (hCG) in normal and abnormal pregnancies. Reprod Biol Endocrinol. 2015;13:14.
