SKU LUM-HEX-2 · C₄₇H₅₈N₁₂O₆ · 887.04 g/mol · CAS 140703-51-1
A synthetic hexapeptide growth-hormone secretagogue and ghrelin-receptor agonist. Studied for cardiovascular and pituitary-axis pharmacology.
Purity (HPLC)
≥ 99.18%
Net peptide
5.00 mg ± 2%
Endotoxin
< 0.5 EU/mg
Format
Lyophilized vial
Storage
−20 °C, desiccated
Shelf life
24 months from MFG
$110CAD/ 10 mg vial
In stock · Lot LM-2705
Qty
Add $300 for Free shipping
HPLC + MS verified per lot
~4 days to your door
COA bundled with shipment
Lot samples retained 5 years
Overview
Hexarelin is a synthetic hexapeptide that activates both the GHS-R1a (ghrelin receptor) and CD36, distinguishing it from more selective ghrelin-receptor agonists. The dual mechanism is investigated for cardiovascular research alongside its primary GH-releasing activity.
Each vial is lyophilized from acetate buffer, sealed under nitrogen, and shipped ~4 days from our lab.
Research applications
GHS-R1a and CD36 binding-affinity assays, pituitary GH-release potentiation studies, cardiomyocyte protection screens, and comparative ghrelin-receptor pharmacology.
Sold for laboratory research only. This material is not a drug, food, or cosmetic and is not intended for diagnostic, therapeutic, or recreational use.
Identity
Parameter
Value
Sequence
His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH₂
Molecular formula
C₄₇H₅₈N₁₂O₆
Molecular weight
887.04 g/mol
CAS number
140703-51-1
Length
6 residues
Quality
Test
Specification
HPLC purity
99.12%
Mass confirmation
ESI-MS within 0.5 Da
Net peptide content
≥ 80% by AAA
Endotoxin
< 0.5 EU/mg (LAL)
Bioburden
< 10 CFU/g
Residual TFA
< 1.0%
Lot LM-2705
Manufactured 04 Mar 2026 · Released 11 Mar 2026 · Tested by Lumera QC, Canada. Retain samples held under storage spec for five years from release date.
Verification
Method
Result
RP-HPLC at 220 nm
99.12% main peak
ESI-MS (positive)
887.0 Da (theor. 887.04)
Amino acid analysis
82.1% net peptide
LAL endotoxin
< 0.05 EU/mg
Karl Fischer (water)
2.8% w/w
Reconstitution
Allow vial to reach room temperature before opening (≥ 20 minutes). Reconstitute with 1.0–2.5 mL of sterile bacteriostatic water (0.9% benzyl alcohol). Inject solvent slowly down the inner wall of the vial; do not direct stream onto the lyophilized cake.
Swirl gently for 30 seconds. Do not vortex. Allow to dissolve for 5 minutes; clarity should be complete with no visible particulates.
Storage after reconstitution
Reconstituted solution is stable for 28 days at 2–8 °C in original vial. For longer storage, aliquot into low-binding tubes and hold at −80 °C; avoid repeated freeze-thaw cycles. Discard if turbidity, color change, or particulate matter is observed.
Selected references
Locatelli V et al. Effect of GH-releasing hexapeptide (GHRP-6) on GH secretion. J Endocrinol. 1994;142(1):65–71.
Bodart V et al. CD36 mediates the cardiovascular action of growth hormone-releasing peptides in the heart. Circ Res. 2002;90(8):844–849.
Mao Y et al. Hexarelin treatment in male ghrelin knockout mice. J Endocrinol. 2014;220(2):217–227.
