Cyanocobalamin (Vitamin B12) is the synthetic cobalt-centered corrinoid form of the B12 family of cofactors. In vivo it is converted to methylcobalamin and adenosylcobalamin, the active forms used as cofactors for methionine synthase and methylmalonyl-CoA mutase.
Lumera supplies cyanocobalamin in sterile solution for in-vitro biochemistry research. Vials shipped at 2-8 °C from our lab.
Sold for laboratory research only. This material is not a drug, food, or cosmetic and is not intended for diagnostic, therapeutic, or recreational use.
Identity
Parameter
Value
Sequence
Cyanocobalamin, cobalt-centered corrinoid
Molecular formula
C₆₃H₈₈CoN₁₄O₁₄P
Molecular weight
1355.37 g/mol
CAS number
68-19-9
Length
Cobalt-corrinoid coenzyme (not a peptide)
Quality
Test
Specification
HPLC purity
USP grade
Certificate of Analysis
The lot-specific COA for this product is available on request. Email support@lumerapeptide.com with your batch number and we will send it.
Allow vial to reach room temperature before opening (≥ 20 minutes). Reconstitute with 1.0-2.5 mL of sterile bacteriostatic water (0.9% benzyl alcohol). Inject solvent slowly down the inner wall of the vial; do not direct stream onto the lyophilized cake.
Swirl gently for 30 seconds. Do not vortex. Allow to dissolve for 5 minutes; clarity should be complete with no visible particulates.
Storage after reconstitution
Reconstituted solution is stable for 28 days at 2-8 °C in original vial. For longer storage, aliquot into low-binding tubes and hold at −80 °C; avoid repeated freeze-thaw cycles. Discard if turbidity, color change, or particulate matter is observed.
Selected references
Banerjee R, Ragsdale SW. The many faces of vitamin B12. Annu Rev Biochem. 2003;72:209-247.
Green R et al. Vitamin B12 deficiency. Nat Rev Dis Primers. 2017;3:17040.
Hannibal L et al. Biomarkers and algorithms for the diagnosis of vitamin B12 deficiency. Front Mol Biosci. 2016;3:27.
