Is Glutathione from Lumera Labs HPLC verified?

Yes. Every Glutathione lot Lumera Labs ships is HPLC-purity tested at synthesis and retested by Janoshik Analytical before release. The lot-specific Certificate of Analysis is available on request.

How is Glutathione shipped?

Glutathione is lyophilized at synthesis, sealed under nitrogen, and shipped across Canada through Canada Post Xpresspost. Free shipping over $300 CAD; ~4 days transit Canada-wide.

Where can I see the COA for Glutathione?

Lot-specific Certificate of Analysis available on request — email us with your order number and the batch from the vial and we will send the report.

What does HPLC-verified mean?

Every lot we sell is tested by an independent third-party lab (Janoshik Analytical) using High-Performance Liquid Chromatography. The Certificate of Analysis reports purity, peptide content by mass, and identity.

How is it shipped within Canada?

Canada Post Xpresspost. Most Canadian addresses arrive in ~4 days from dispatch. Free shipping on Canadian orders over $300; otherwise a flat $25 shipping fee applies.

Is this for human or animal use?

All Lumera products are supplied strictly for laboratory research use only — in-vitro reference standards. By ordering you confirm you have read and accept our Research Use Declaration.

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Home / Catalog / Nutrition / Glutathione 1500 mg

Longevity · Reduced Glutathione

Glutathione

SKU LUM-GLUTA-1500 · C₁₀H₁₇N₃O₆S · 307.32 g/mol · CAS 70-18-8

Reduced L-glutathione (GSH) — the tripeptide thiol antioxidant central to phase-II conjugation, redox buffering, and mitochondrial signaling. Lyophilized 1500 mg vial for in-vitro reconstitution and cell-culture research.

Purity (HPLC): ≥ 99.5%
Net peptide: 1500 mg ± 2%
Endotoxin: < 0.5 EU/mg
Format: Lyophilized vial
Storage: −20 °C, desiccated
Shelf life: 24 months from MFG

$60CAD / 1500 mg vial

In stock · Lot LM-2772

Add $300 for Free shipping

HPLC + MS verified per lot
~4 days to your door
COA bundled with shipment
Lot samples retained 5 years

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Overview

Reduced L-glutathione (GSH) is the tripeptide γ-L-glutamyl-L-cysteinylglycine, the most abundant intracellular thiol antioxidant. It maintains the cellular redox state via the GSH/GSSG cycle, conjugates electrophiles in phase-II detoxification through glutathione-S-transferase, and reduces peroxides through glutathione peroxidase.

Lumera supplies reduced glutathione as a lyophilized 1500 mg vial for in-vitro reconstitution. Store at −20 °C, desiccated; reconstitute to working concentration in sterile water immediately before use.

Research applications

B12-dependent enzyme assays (methionine synthase, methylmalonyl-CoA mutase), folate-cycle metabolomics, and corrinoid-cofactor structure studies.

Sold for laboratory research only. This material is not a drug, food, or cosmetic and is not intended for diagnostic, therapeutic, or recreational use.

Identity

Parameter	Value
Sequence	γ-L-Glu–L-Cys–Gly (tripeptide, free thiol)
Molecular formula	C₆₃H₈₈CoN₁₄O₁₄P
Molecular weight	307.32 g/mol
CAS number	68-19-9
Length	Cobalt-corrinoid coenzyme (not a peptide)

Quality

Test	Specification
HPLC purity	USP grade
Mass confirmation	ESI-MS within 0.5 Da
Net peptide content	≥ 80% by AAA
Endotoxin	< 0.5 EU/mg (LAL)
Bioburden	< 10 CFU/g
Residual TFA	< 1.0%

Lot LM-2772

Manufactured 04 Mar 2026 · Released 11 Mar 2026 · Tested by Lumera QC, Canada. Retain samples held under storage spec for five years from release date.

Verification

Method	Result
RP-HPLC at 220 nm	USP grade main peak
ESI-MS (positive)	307.3 Da (theor. 307.32)
Amino acid analysis	82.1% net peptide
LAL endotoxin	< 0.05 EU/mg
Karl Fischer (water)	2.8% w/w

Reconstitution

Allow vial to reach room temperature before opening (≥ 20 minutes). Reconstitute with 1.0–2.5 mL of sterile bacteriostatic water (0.9% benzyl alcohol). Inject solvent slowly down the inner wall of the vial; do not direct stream onto the lyophilized cake.

Swirl gently for 30 seconds. Do not vortex. Allow to dissolve for 5 minutes; clarity should be complete with no visible particulates.

Storage after reconstitution

Reconstituted solution is stable for 28 days at 2–8 °C in original vial. For longer storage, aliquot into low-binding tubes and hold at −80 °C; avoid repeated freeze-thaw cycles. Discard if turbidity, color change, or particulate matter is observed.

Selected references

Meister A, Anderson ME. Glutathione. Annu Rev Biochem. 1983;52:711–760.

Forman HJ, Zhang H, Rinna A. Glutathione: overview of its protective roles, measurement, and biosynthesis. Mol Aspects Med. 2009;30(1-2):1–12.

Lu SC. Regulation of glutathione synthesis. Mol Aspects Med. 2009;30(1-2):42–59.

Citing this material

Reduced L-Glutathione (GSH) reference standard, ≥99% (HPLC), Lumera Labs Inc., Cat. No. LUM-GLUTA-1500, Lot LM-2772.

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