Melanotan II is a synthetic cyclic seven-residue analog of α-MSH that activates MC1R, MC3R, MC4R, and MC5R with broad affinity. The cyclization confers metabolic stability relative to linear α-MSH analogs. It is studied as a tool compound in melanocortin-receptor structure-activity research.
Each vial is lyophilized from acetate buffer, sealed under nitrogen, and shipped ~4 days from our lab.
Research applications
Comparative MC1/3/4/5R agonism assays, melanocyte tyrosinase induction studies, and structural pharmacology of the cyclic melanocortin scaffold.
Sold for laboratory research only. This material is not a drug, food, or cosmetic and is not intended for diagnostic, therapeutic, or recreational use.
Identity
Parameter
Value
Sequence
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂
Molecular formula
C₅₀H₆₉N₁₅O₉
Molecular weight
1024.18 g/mol
CAS number
121062-08-6
Length
7 residues (cyclic)
Quality
Test
Specification
HPLC purity
99.14%
Certificate of Analysis
The lot-specific COA for this product is available on request. Email support@lumerapeptide.com with your batch number and we will send it.
Allow vial to reach room temperature before opening (≥ 20 minutes). Reconstitute with 1.0-2.5 mL of sterile bacteriostatic water (0.9% benzyl alcohol). Inject solvent slowly down the inner wall of the vial; do not direct stream onto the lyophilized cake.
Swirl gently for 30 seconds. Do not vortex. Allow to dissolve for 5 minutes; clarity should be complete with no visible particulates.
Storage after reconstitution
Reconstituted solution is stable for 28 days at 2-8 °C in original vial. For longer storage, aliquot into low-binding tubes and hold at −80 °C; avoid repeated freeze-thaw cycles. Discard if turbidity, color change, or particulate matter is observed.
