SKU LUM-MT2-10 · C₅₀H₆₉N₁₅O₉ · 1024.18 g/mol · CAS 121062-08-6
A cyclic heptapeptide non-selective melanocortin-receptor agonist (MC1/3/4/5R). Studied for pigmentation pathways and structural pharmacology.
Purity (HPLC)
≥ 99.15%
Net peptide
5.00 mg ± 2%
Endotoxin
< 0.5 EU/mg
Format
Lyophilized vial
Storage
−20 °C, desiccated
Shelf life
24 months from MFG
$55CAD/ 10 mg vial
In stock · Lot LM-2745
Qty
Add $300 for Free shipping
HPLC + MS verified per lot
~4 days to your door
COA bundled with shipment
Lot samples retained 5 years
Overview
Melanotan II is a synthetic cyclic seven-residue analog of α-MSH that activates MC1R, MC3R, MC4R, and MC5R with broad affinity. The cyclization confers metabolic stability relative to linear α-MSH analogs. It is studied as a tool compound in melanocortin-receptor structure-activity research.
Each vial is lyophilized from acetate buffer, sealed under nitrogen, and shipped ~4 days from our lab.
Research applications
Comparative MC1/3/4/5R agonism assays, melanocyte tyrosinase induction studies, and structural pharmacology of the cyclic melanocortin scaffold.
Sold for laboratory research only. This material is not a drug, food, or cosmetic and is not intended for diagnostic, therapeutic, or recreational use.
Identity
Parameter
Value
Sequence
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂
Molecular formula
C₅₀H₆₉N₁₅O₉
Molecular weight
1024.18 g/mol
CAS number
121062-08-6
Length
7 residues (cyclic)
Quality
Test
Specification
HPLC purity
99.14%
Mass confirmation
ESI-MS within 0.5 Da
Net peptide content
≥ 80% by AAA
Endotoxin
< 0.5 EU/mg (LAL)
Bioburden
< 10 CFU/g
Residual TFA
< 1.0%
Lot LM-2745
Manufactured 04 Mar 2026 · Released 11 Mar 2026 · Tested by Lumera QC, Canada. Retain samples held under storage spec for five years from release date.
Verification
Method
Result
RP-HPLC at 220 nm
99.14% main peak
ESI-MS (positive)
1024.2 Da (theor. 1024.18)
Amino acid analysis
82.1% net peptide
LAL endotoxin
< 0.05 EU/mg
Karl Fischer (water)
2.8% w/w
Reconstitution
Allow vial to reach room temperature before opening (≥ 20 minutes). Reconstitute with 1.0–2.5 mL of sterile bacteriostatic water (0.9% benzyl alcohol). Inject solvent slowly down the inner wall of the vial; do not direct stream onto the lyophilized cake.
Swirl gently for 30 seconds. Do not vortex. Allow to dissolve for 5 minutes; clarity should be complete with no visible particulates.
Storage after reconstitution
Reconstituted solution is stable for 28 days at 2–8 °C in original vial. For longer storage, aliquot into low-binding tubes and hold at −80 °C; avoid repeated freeze-thaw cycles. Discard if turbidity, color change, or particulate matter is observed.
